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Research Activity

  • Epigenetic Mechanisms in Reprogramming
    Investigating how epigenetic regulation influences cellular reprogramming to enhance efficiency and improve iPSC generation.

     

  • Scalable Gene Editing
    Advancing high-throughput and precision gene modification techniques to enable robust genome engineering applications.

     

  • Automated Disease Modeling
    Utilizing automation to optimize scalable and reproducible disease modeling for translational research.

     

  • Cellular Resilience and Adaptation
    Exploring mechanisms that regulate cellular stress responses and stability, with implications for regenerative medicine and disease resistance.

     

  • Developmental Immune Defense Strategies
    Investigating early cellular mechanisms that contribute to immune modulation and protective responses in developing tissues.

     

  • Adaptive Immunotherapy Engineering
    Enhancing personalized cell therapy approaches by optimizing functional immune cell selection and expansion strategies.

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Core Services

The Center at UCLA provides cutting-edge services focused on generating pluripotent stem cells from patient samples; genome engineering and editing services for basic core and preclinical research; and chemical and CRISPR screenings including CRISPR mediated activation and/or inhibition of genes.

FUNDING

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Email

Address

UCLA - CHS 36 - 125/133/143

 650 Charles E Young Dr S, Los Angeles, CA 90095

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© 2022-2024 by UCLA - Stem Cell Engineering Center (HSCGEC)

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